Annotated List Of
Symptoms And Health Problems Associated With Gluten Sensitivity.
To Temporary Main Gluten Page To Essay List
“Be careful reading
medical books. You might die of a mis-print.” -- Mark Twain
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Short Cuts: |
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Site Disclaimer (separate
page) |
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The Basics (separate page) |
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The Short List (this page) |
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The Long List (this page) |
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A
Medium List (celiac.com) |
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Some
Symptom Lists From Established Medical Sites (this page) |
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See also: |
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Sprue-nik Press
Medical/Research Articles Index (http://www.enabling.org/) |
Introduction
Many
medical institutions provide lists of symptoms and health problems associated
with Celiac Disease and gluten sensitivity.
The list I present here is a compilation of several
such lists. I have found these
lists lacking in explanations of how gluten is related to each symptoms or condition. Furthermore, these lists lack descriptions
of the conditions for the non-medical person (“What the heck is ‘aphthous
stomatitis’, anyway?”). I am
developing this list not only for the reader’s interest, but also for my own
easy reference.
The
very length of the lists made me dubious at first – how could one thing cause
so much? Even more so, how could one
thing cause or contribute to opposite problems like skinniness
and obesity, diarrhea
and constipation, insanity and genius? The very idea was hard to swallow, as it were. Once I could no longer deny that gluten does
indeed cause and contribute to many problems as I found them in my body, I
decided to teach myself how wheat gluten can do it all.
Let
me point out now that having none of the following conditions is no proof that
you are free from sensitivity to gluten.
Neither is having any of these symptoms proof that you are
sensitive. But all of these symptoms
(and more not listed) should cause suspicion of gluten intolerance – some
should cause a LOT of suspicion.
Celiacs who have chronic symptoms are expected to develop even more
chronic symptoms if they don’t stop eating gluten.[1] (Maybe a new one every two to six years,
give or take?) All research papers
cited in the following annotations conclude that ALL people with the listed
conditions should be tested.
This
annotated list is intended to be informative rather than diagnostic – I want to
raise curiosity and suspicion. Readers
are most strongly encouraged to further study any listed symptoms they
recognize in themselves, their blood relatives, and their friends. Your doctor
can only work with you 15 minutes at a time – You are with yourself at least
most of the time. Caveat: Even though
some very serious factors other than gluten sensitivity (such as tumors) can be
involved with many of these problems, gluten sensitivity is common if not
pandemic in its association with the listed symptoms and conditions.
Because
a number of common factors of gliadin sensitivity lie under many different
symptoms and diseases, I have prepared a short essay titled The Basics
Factors of Gluten Sensitivity and Celiac Disease. The following descriptions make many references to the factors
discussed in that essay.
If
you are interested in a specific condition for which you know the name, look in
The
Long List. Otherwise, please check
out The
Short List, which is organized by general subjects of high interest. The initial sources for the conditions I
list here came from many lists on medical sites – if you are interested, please
see the Symptom
Lists From Established Medical Sites a ways down this page.
(Developer’s Note: This annotation is an ongoing project. I have 3+ years of research collected, but
little time now to put it on line.
Subjects that friends or family ask about have priority. Underlined
entries are hypertext links to annotation pages that are at least partially
developed.)
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Arthritis |
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Depression/Mood
Problems |
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Fatigue |
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Weak
Bones |
Eccentricity/Genius |
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Muscle
Pain |
Social
Problems |
Vitamin
Deficiencies |
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Bad
Teeth |
Shortness/Delayed
Growth |
Pancreas/Gall
Bladder |
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Cancer/Leukemia |
Frequent
Colds/Lung Infections |
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Some conditions appear more than once in this list where I may include both a technical name and multiple common names for a single condition.
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Abdominal
Pain, Recurrent |
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ALS |
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Alzheimer’s
AI |
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Addison’s
disease (loss of adrenal glands) AI |
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Anxiety
and depression |
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Arthralgia
or arthropathy |
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Arthritis |
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Asthma
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Bi-Polar
Disorder |
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Cancer,
Lymphoma, Enteropathy-associated T cell |
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Candidiasis |
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Carcinoma
of the oropharynx, esophagus, and small bowel |
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Carpal
Tunnel/Cubital Tunnel |
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Cistitis,
intersitial |
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Chronic
Fatigue |
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Cluster
Headaches |
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Concentration
Problems |
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Dementia
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Depression
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Divorce |
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Ear
Infections / Ear Itching & Drainage |
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Fatigue
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Female
Reproductive system problems. |
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Fibromyalgia
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Fibrosing
alveolitis |
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Frequent
respiratory infections |
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Hay
Fever |
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Hepatitis,
Autoimmune (liver problem) |
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Hypertension |
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Hypertransaminasemia
(liver problem) |
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Hypoplasia
(Bad Teeth) |
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Hypotonia |
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Idiopathic
pulmonary hemosiderosis |
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IgA
deficiency |
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IgA
nephropathy, mesangial |
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Irritability |
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Jejunoileitis,
Ulcerative |
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Joint
Pain, Chronic |
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Leukemia |
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Lupus,
Systemic lupus erythematosus |
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Marriage
Problems |
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Memory
Problems |
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Muscle
Twitch |
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Myasthenia
gravis |
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Myocarditis
(heart) |
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Pancreatitis,
Recurrent |
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Pericarditis,
Recurrent (heart) |
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Polymyositis |
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Polyneuropathy
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Primary
biliary cirrhosis |
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Psychiatric
disorders |
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Pulmonary
hemosiderosis |
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Rheumatoid
arthritis |
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Schizophrenia |
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Self-Medication |
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Sexual
Problems |
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Short
stature |
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Skin
Sensitivity and Pain |
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Spinocerebellar
syndrome |
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Social
Difficulties |
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Stress/Tension
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Stroke
(basal) |
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Tendon
Pain Chronic |
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Tetany
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Thrombocytosis
(hyposplenism) |
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Transaminase,
elevated concentration = liver problem |
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Vasculitis |
(sources for much of the above list)
Celiac Features and Associated Conditions from The New England Journal of Medicine
COMMON FEATURES ASSOCIATED CONDITIONS
Adults Definite associations
Iron-deficiency anemia Dermatitis herpetiformis
Diarrhea IgA deficiency
LESS COMMON FEATURES Type 1 diabetes
Children Autoimmune thyroid disease
Diarrhea Sjögren’s syndrome
Failure to thrive Microscopic colitis
Abdominal distention Rheumatoid arthritis
General features Down’s syndrome
Short stature IgA nephropathy
Delayed puberty Possible associations
Gastrointestinal features Congenital heart disease
Recurrent aphthous stomatitis Recurrent pericarditis
Recurrent abdominal pain Sarcoidosis
Steatorrhea Cystic fibrosis
Extraintestinal features Fibrosing alveolitis
Folate-deficiency anemia Lung cavities
Osteopenia or osteoporosis Pulmonary hemosiderosis
Dental-enamel hypoplasia Inflammatory bowel disease
Vitamin K deficiency Autoimmune hepatitis
Hypertransaminasemia Primary biliary cirrhosis
Thrombocytosis (hyposplenism) Addison’s disease
Arthralgia or arthropathy Systemic lupus erythematosus
Polyneuropathy Vasculitis
Ataxia Polymyositis
Epilepsy (with or w/o cerebral calcification) Myasthenia gravis
Infertility Schizophrenia
Recurrent abortions COMPLICATIONS
Anxiety and depression Refractory sprue
Follicular keratosis Enteropathy-associated T-cell lymphoma
Alopecia Carcinoma of the oropharynx, esophagus, and small bowel
Ulcerative jejunoileitis
Collagenous sprue
Celiac Symptoms from Web MD:
· Diarrhea.
· Underweight
· Gas
· Delayed onset of puberty.
· Delayed growth.
· Problems with memory and concentration.
· Depression.
· Frequent respiratory infections.
· Anemia.
· Fatigue
· Bone problems.
· Female Reproductive system problems.
Celiac Symptoms from Celiac Sprue Association/USA, Inc.
· Muscle Twitch
· Irritability.
· Diarrhea.
· Underweight
· Gas
· Delayed growth.
· Problems with memory and concentration.
· Anemia.
· Fatigue
· Bone problems.
A good, if short list from the University
of Chicago Celiac Disease Program.
Table 1. — Main Presentations of Extraintestinal (or ‘Atypical’) Celiac Disease
· Dermatitis herpetiformis
· Permanent enamel hypoplasia
· Iron deficiency anemia that is resistant to oral iron therapy
· Short stature, delayed puberty
· Chronic hepatitis with hypertransaminasemia
· Primary biliary cirrhosis
· Arthritis
· Osteopenia/Osteoporosis
· Epilepsy with occipital calcifications
· Primary ataxia
· Psychiatric disorders
· Infertility
American Journal of Clinical Nutrition
The widening spectrum of celiac disease
TABLE 2. Presentations of gluten-sensitive enteropathy
Gastrointestinal symptoms Nongastrointestinal symptoms
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Steatorrhea Dermatitis herpetiformis
Duodenal obstruction Infertility or fetal loss
Osmotic diarrhea Anemia
Elevated transaminase concentrations Dementia
Secretory diarrhea Folate or iron deficiency
Recurrent pancreatitis Spinocerebellar syndrome
Weight loss Neuropathy
Occult blood Tetany
Constipation Osteoporosis
Enteropathy-associated T cell lymphoma Arthralgia
Bloating Abdominal pain Developmentally synchronous dental enamel defects
Failure to thrive Fatigue
Vomiting Osteomalcia
Dyspepsia Seizures
Depression
Brittleness of diabetes control
● abdominal pain
● diarrhea
● Rectal bleeding
● weight loss
● Fever
● delayed development, stunted growth
● High white blood cell
Inflammatory Bowel Disease Symptoms from Web MD (Ulcerative colitis and Crohn's disease)
● abdominal pain
● Diarrhea
● Constipation
● Loss of appetite.
● Fever
● Weight loss
● anemia
● Ulcers in the mouth.
● Nutritional deficiencies
● Bowel obstruction
● Bowel ulcers
● Small tears (fissures) in the anus.
Complications of Inflammatory Bowel Disease outside the digestive tract
● Joint pain
● eye problems
● Eye symptoms such as cataracts, ulcers on the cornea, inflammation of the iris and blood vessels (uveitis), and inflammation of the white part of the eyes (sclera). Eye problems occur in less than 10% of people who have IBD.
● skin rash
● Liver
● Urinary tract complications
● Delayed childhood Development
● Blood Clots
● Osteoporosis.
● Hypothyroidism
● fatigue
● weight gain
● constipation
● dry skin
● dry hair
● hair loss
● high cholesterol
● drastically reduced sex drive
● brain fog
● full-feeling neck
● swollen hands and feet
● muscle pain
● carpal tunnel syndrome
● tendonitis
Sjögren's Syndrome
● Dry, gritty, sandy, or itchy feeling in your eyes
● A "filmy" sensation in your eyes that interferes with vision
● Thick, ropelike strands of dried mucus in your eyes when you wake up in the morning
● Redness and decreased tearing
● Bright lights may bother your eyes
● Inflamed eyelids (blepharitis)
● Eye fatigue
● Decreased amount of saliva
● Difficulty swallowing food without also drinking a liquid
● Abnormal sense of taste
● Sores (fissures) on the tongue and lips
● Numerous cavities and gum (periodontal) disease caused by rapid tooth decay
● Decreased sense of taste and smell
● Mouth may feel full of cotton
● Enlarged saliva glands under the chin (submandibular glands) and in front of the ears (parotid glands) that can be sore and tender.
● Exceptionally dry skin with decreased sweat production
● Skin rashes, bumps, and bruises that can be sensitive to light.
● Vaginal dryness, causing discomfort, itching, and painful intercourse.
● Increased fatigue
● A yeast infection in the mouth (thrush).
● Burning sensation (heartburn) in the chest or throat caused by abnormal backflow of acid and other digestive juices.
● Dry nose and throat, which can lead to sinus infections, bronchitis, and pneumonia
● Allergic reactions to medications, particularly to penicillin and sulfur compounds
● Joint and muscle pain
● Thyroid problems such as hypothyroidism or hyperthyroidism
● Nervous system problems, such as numbness or tingling in extremities, or peripheral neuropathies
● Cold, numb, painful fingers and hands (Raynaud's phenomenon).
● Pain and difficulty with dentures, which may lead to dental restorations
● Increased physical and mental activity and energy
● Heightened mood, exaggerated optimism and self-confidence
● Excessive irritability, aggressive behavior
● Decreased need for sleep without experiencing fatigue
● Grandiose delusions, inflated sense of self-importance
● Racing speech, racing thoughts, flight of ideas
● Impulsiveness, poor judgment, distractibility
● Reckless behavior
● In the most severe cases, delusions and hallucinations
● Prolonged sadness or unexplained crying spells
● Significant changes in appetite and sleep patterns
● Irritability, anger, worry, agitation, anxiety
● Pessimism, indifference
● Loss of energy, persistent lethargy
● Feelings of guilt, worthlessness
● Inability to concentrate, indecisiveness
● Inability to take pleasure in former interests, social withdrawal
● Unexplained aches and pains
● Recurring thoughts of death or suicide
Hey, Calontir!
[1] “Duration
of exposure to gluten and risk for autoimmune disorders in patients with celiac
disease. SIGEP Study Group for Autoimmune Disorders in Celiac Disease.”,
Ventura A, Magazzu G, Greco L., Department of Pediatrics, University of Trieste,
IRCCS Burlo-Garofolo, Trieste, Italy, Gastroenterology. 1999
Aug;117(2):297-303.