Annotated List Of Symptoms And Health Problems Associated With Gluten Sensitivity.

 

To Temporary Main Gluten Page                                                                              To Essay List

 

“Be careful reading medical books. You might die of a mis-print.” -- Mark Twain

 

Short Cuts:

Site Disclaimer (separate page)

The Basics (separate page)

The Short List (this page)

The Long List (this page)

A Medium List (celiac.com)

Some Symptom Lists From Established Medical Sites (this page)

See also:

Sprue-nik Press Medical/Research Articles Index (http://www.enabling.org/)

Introduction

Many medical institutions provide lists of symptoms and health problems associated with Celiac Disease and gluten sensitivity.  The list I present here is a compilation of several such lists.  I have found these lists lacking in explanations of how gluten is related to each symptoms or condition.  Furthermore, these lists lack descriptions of the conditions for the non-medical person (“What the heck is ‘aphthous stomatitis’, anyway?”).  I am developing this list not only for the reader’s interest, but also for my own easy reference. 

 

The very length of the lists made me dubious at first – how could one thing cause so much?  Even more so, how could one thing cause or contribute to opposite problems like skinniness and obesity, diarrhea and constipation, insanity and genius?  The very idea was hard to swallow, as it were.  Once I could no longer deny that gluten does indeed cause and contribute to many problems as I found them in my body, I decided to teach myself how wheat gluten can do it all.

 

Let me point out now that having none of the following conditions is no proof that you are free from sensitivity to gluten.  Neither is having any of these symptoms proof that you are sensitive.  But all of these symptoms (and more not listed) should cause suspicion of gluten intolerance – some should cause a LOT of suspicion.  Celiacs who have chronic symptoms are expected to develop even more chronic symptoms if they don’t stop eating gluten.[1] (Maybe a new one every two to six years, give or take?)  All research papers cited in the following annotations conclude that ALL people with the listed conditions should be tested.

 

This annotated list is intended to be informative rather than diagnostic – I want to raise curiosity and suspicion.  Readers are most strongly encouraged to further study any listed symptoms they recognize in themselves, their blood relatives, and their friends. Your doctor can only work with you 15 minutes at a time – You are with yourself at least most of the time.  Caveat: Even though some very serious factors other than gluten sensitivity (such as tumors) can be involved with many of these problems, gluten sensitivity is common if not pandemic in its association with the listed symptoms and conditions. 

 

Because a number of common factors of gliadin sensitivity lie under many different symptoms and diseases, I have prepared a short essay titled The Basics Factors of Gluten Sensitivity and Celiac Disease.  The following descriptions make many references to the factors discussed in that essay.

 

If you are interested in a specific condition for which you know the name, look in The Long List.  Otherwise, please check out The Short List, which is organized by general subjects of high interest.  The initial sources for the conditions I list here came from many lists on medical sites – if you are interested, please see the Symptom Lists From Established Medical Sites a ways down this page.

 

The Short List:

(Developer’s Note:  This annotation is an ongoing project.  I have 3+ years of research collected, but little time now to put it on line.  Subjects that friends or family ask about have priority. Underlined entries are hypertext links to annotation pages that are at least partially developed.)

Diabetes

Headaches/Migraines

Rashes/Skin Problems

Arthritis

Brain/Nerve Damage

Seizures

Thyroid Disease 

Developmental Disorders

Heart Disease

Sexual Issues

Depression/Mood Problems

Digestive Problems

Eye Problems 

Hair Loss/White Hair

Food Cravings

Birth Defects

Alcoholism/Drugs

Skinniness/Obesity

Fatigue

Infertility, Miscarriage and other Reproductive Problems

Mouth/Dental

Lungs/Colds

Malabsorption

Weak Bones

Dizziness/Clumsiness

Eccentricity/Genius

Muscle Pain

Social Problems

Vitamin Deficiencies

Bad Teeth

Shortness/Delayed Growth

Pancreas/Gall Bladder

Cancer/Leukemia

Frequent Colds/Lung Infections

 

 

The Long List:

Some conditions appear more than once in this list where I may include both a technical name and multiple common names for a single condition.

Abdominal Distention

Abdominal Pain, Recurrent

Acid Reflux

Acne

ADD/ADHD

AIDS

ALS

Alzheimer’s AI

Addison’s disease (loss of adrenal glands) AI

Alopecia Areata (hair loss)

Anemia

Anxiety and depression

Aphthous stomatitis, Recurrent AI Mal

Arthralgia or arthropathy

Arthritis

Asperger's Syndrome

Asthma

Ataxia

Autism

Bad Teeth:

Bi-Polar Disorder

Bird-fancier’s lung

Birth Defects

Blindness

Bloating

Bone problems

Bruising, Vitamin K deficiency

Cancer, Lymphoma, Enteropathy-associated T cell

Candidiasis

Carcinoma of the oropharynx, esophagus, and small bowel

Carpal Tunnel/Cubital Tunnel

Cistitis, intersitial

Celiac Disease

Chronic Fatigue

Clumsiness

Cluster Headaches

Colds, Frequent

Colitis, Microscopic and collagenous

Collagenous sprue

Concentration Problems

Constipation

Crohn's Disease

Cystic Fibrosis

Delayed growth

Delayed puberty

Dementia

Depression

Dermatitis Herpetiformis

Diabetes Type 1 Mellitus

Diabetes Type 2

Diabetes, brittleness of control

Diarrhea

Diarrhea, Osmotic

Diarrhea, Secretory

Diverticulosis / Diverticulitis

Divorce

Dizziness

Down Syndrome

Drug Use

Dry Skin

Duodenal Obstruction

Dyspepsia

Ear Infections / Ear Itching & Drainage

Epilepsy (with or w/o cerebral/ occipital calcification)

Eczema

Failure to thrive

Fatigue

Female Reproductive system problems.

Fibromyalgia

Fibrosing alveolitis

Folate-deficiency anemia

Follicular keratosis

Food Cravings

Frequent respiratory infections

Gas

Gastroparesis (Slow Stomach)

Grave's Disease

Hair Loss

Hay Fever

Headaches

Heart Disease

Heel Fissures

Hepatitis, Autoimmune (liver problem)

Huntington's Disease

Hyperactivity

Hypertension

Hypertransaminasemia (liver problem)

Hypoglycemia

Hypoplasia (Bad Teeth)

Hypotonia

Idiopathic pulmonary hemosiderosis

IgA deficiency

IgA nephropathy, mesangial

Infertility

Inflammatory bowel disease

Iron deficiency

Irritability

Irritable Bowel Syndrome (IBS)

Jejunoileitis, Ulcerative

Joint Pain, Chronic

Lactose Intolerance

Leaky Gut

Leukemia

Lung Cavities/Lung Infections

Lupus, Systemic lupus erythematosus

Marriage Problems

Memory Problems

Migraine Headaches

Miscarriages, Abortions

Muscle Twitch

Myasthenia gravis

Myocarditis (heart)

Neuropathy

Night Blindness

Obesity

Occult (hidden) blood in stool

Osteomalcia

Osteoporosis/Osteopenia

Pancreatitis, Recurrent

Pericarditis, Recurrent (heart)

Polymyositis

Polyneuropathy

Potbelly

Primary biliary cirrhosis

Psoriasis

Psychiatric disorders

Pulmonary hemosiderosis

Recurrent abortions

Refractory sprue

Rheumatoid arthritis

Sarcoidosis

Scaly Skin

Schizophrenia

Seizures

Self-Medication

Sexual Problems

Short stature

Sinusitis

Sjögren’s Syndrome

Skin Rashes

Skin Sensitivity and Pain

Skinniness (hollow leg)

Slow Stomach (Gastroparesis)

Snow White Hair

Spinocerebellar syndrome

Social Difficulties

Split Heels

Steatorrhea

Stress/Tension

Stroke (basal)

Tendon Pain Chronic

Tetany

Thrombocytosis (hyposplenism)

Thyroid Problems

Transaminase, elevated concentration = liver problem

Vasculitis

Vomiting

Weight Loss

 

 

 

Some Related Symptom Lists From Established Medical Sites:

(sources for much of the above list)

 

Celiac Features and Associated Conditions from The New England Journal of Medicine

COMMON FEATURES                                         ASSOCIATED CONDITIONS

Adults                                                                    Definite associations

Iron-deficiency anemia                                            Dermatitis herpetiformis

Diarrhea                                                                  IgA deficiency

LESS COMMON FEATURES                                    Type 1 diabetes

Children                                                                 Autoimmune thyroid disease

Diarrhea                                                                  Sjögren’s syndrome

Failure to thrive                                                       Microscopic colitis

Abdominal distention                                              Rheumatoid arthritis

General features                                                      Down’s syndrome

Short stature                                                           IgA nephropathy

Delayed puberty                                                      Possible associations

Gastrointestinal features                                          Congenital heart disease

Recurrent aphthous stomatitis                                  Recurrent pericarditis

Recurrent abdominal pain                                        Sarcoidosis

Steatorrhea                                                             Cystic fibrosis

Extraintestinal features                                             Fibrosing alveolitis

Folate-deficiency anemia                                         Lung cavities

Osteopenia or osteoporosis                                     Pulmonary hemosiderosis

Dental-enamel hypoplasia                                        Inflammatory bowel disease

Vitamin K deficiency                                               Autoimmune hepatitis

Hypertransaminasemia                                             Primary biliary cirrhosis

Thrombocytosis (hyposplenism)                             Addison’s disease

Arthralgia or arthropathy                                         Systemic lupus erythematosus

Polyneuropathy                                                       Vasculitis

Ataxia                                                                     Polymyositis

Epilepsy (with or w/o cerebral calcification)             Myasthenia gravis

Infertility                                                                 Schizophrenia

Recurrent abortions                                            COMPLICATIONS

Anxiety and depression                                           Refractory sprue

Follicular keratosis                                                  Enteropathy-associated T-cell lymphoma

Alopecia                                                                 Carcinoma of the oropharynx, esophagus, and small bowel

                                                                              Ulcerative jejunoileitis

                                                                              Collagenous sprue

 

Celiac Symptoms from Web MD:

·        Diarrhea.

·        Underweight

·        Gas

·        Delayed onset of puberty.

·        Delayed growth.

·        Problems with memory and concentration.

·        Depression.

·        Frequent respiratory infections.

·        Anemia.

·        Fatigue

·        Bone problems.

·        Female Reproductive system problems.

 

Celiac Symptoms from Celiac Sprue Association/USA, Inc.

·        Muscle Twitch

·        Irritability.

·        Diarrhea.

·        Underweight

·        Gas

·        Delayed growth.

·        Problems with memory and concentration.

·        Anemia.

·        Fatigue

·        Bone problems.

 

A good, if short list from the University of Chicago Celiac Disease Program.

Table 1. — Main Presentations of Extraintestinal (or ‘Atypical’) Celiac Disease

·        Dermatitis herpetiformis

·        Permanent enamel hypoplasia

·        Iron deficiency anemia that is resistant to oral iron therapy

·        Short stature, delayed puberty

·        Chronic hepatitis with hypertransaminasemia

·        Primary biliary cirrhosis

·        Arthritis

·        Osteopenia/Osteoporosis

·        Epilepsy with occipital calcifications

·        Primary ataxia

·        Psychiatric disorders

·        Infertility

 

American Journal of Clinical Nutrition

The widening spectrum of celiac disease

TABLE 2. Presentations of gluten-sensitive enteropathy

Gastrointestinal symptoms                              Nongastrointestinal symptoms

--------------------------------------------------------------------------------

Steatorrhea                                                     Dermatitis herpetiformis

Duodenal obstruction                                     Infertility or fetal loss

Osmotic diarrhea                                            Anemia

Elevated transaminase concentrations              Dementia

Secretory diarrhea                                          Folate or iron deficiency

Recurrent pancreatitis                                     Spinocerebellar syndrome

Weight loss                                                    Neuropathy

Occult blood                                                  Tetany

Constipation                                                   Osteoporosis

Enteropathy-associated T cell lymphoma         Arthralgia

Bloating Abdominal pain                                 Developmentally synchronous dental enamel defects

Failure to thrive                                              Fatigue

Vomiting                                                        Osteomalcia

Dyspepsia                                                      Seizures

                                                                      Depression

                                                                      Brittleness of diabetes control

 

 

Crohn's Disease Symptoms from Web MD

      abdominal pain

      diarrhea

      Rectal bleeding

      weight loss

      Fever

      delayed development, stunted growth

      High white blood cell

 

Inflammatory Bowel Disease Symptoms from Web MD (Ulcerative colitis and Crohn's disease)

      abdominal pain

      Diarrhea

      Constipation

      Loss of appetite.

      Fever

      Weight loss

      anemia

      Ulcers in the mouth.

      Nutritional deficiencies

      Bowel obstruction

      Bowel ulcers

      Small tears (fissures) in the anus.

 

 

Complications of Inflammatory Bowel Disease outside the digestive tract

      Joint pain

      eye problems

      Eye symptoms such as cataracts, ulcers on the cornea, inflammation of the iris and blood vessels (uveitis), and inflammation of the white part of the eyes (sclera). Eye problems occur in less than 10% of people who have IBD.

      skin rash

      Liver

      Urinary tract complications

      Delayed childhood Development

      Blood Clots

      Osteoporosis.

 

      Hypothyroidism

      fatigue

      weight gain

      constipation

      dry skin

      dry hair

      hair loss

      high cholesterol

      drastically reduced sex drive

      brain fog

      full-feeling neck

      swollen hands and feet

      muscle pain

      carpal tunnel syndrome

      tendonitis

 


Sjögren's Syndrome

      Dry, gritty, sandy, or itchy feeling in your eyes

      A "filmy" sensation in your eyes that interferes with vision

      Thick, ropelike strands of dried mucus in your eyes when you wake up in the morning

      Redness and decreased tearing

      Bright lights may bother your eyes

      Inflamed eyelids (blepharitis)

      Eye fatigue

      Decreased amount of saliva

      Difficulty swallowing food without also drinking a liquid

      Abnormal sense of taste

      Sores (fissures) on the tongue and lips

      Numerous cavities and gum (periodontal) disease caused by rapid tooth decay

      Decreased sense of taste and smell

      Mouth may feel full of cotton

      Enlarged saliva glands under the chin (submandibular glands) and in front of the ears (parotid glands) that can be sore and tender.

      Exceptionally dry skin with decreased sweat production

      Skin rashes, bumps, and bruises that can be sensitive to light.

      Vaginal dryness, causing discomfort, itching, and painful intercourse.

      Increased fatigue

      A yeast infection in the mouth (thrush).

      Burning sensation (heartburn) in the chest or throat caused by abnormal backflow of acid and other digestive juices.

      Dry nose and throat, which can lead to sinus infections, bronchitis, and pneumonia

      Allergic reactions to medications, particularly to penicillin and sulfur compounds

      Joint and muscle pain

      Thyroid problems such as hypothyroidism or hyperthyroidism

      Nervous system problems, such as numbness or tingling in extremities, or peripheral neuropathies

      Cold, numb, painful fingers and hands (Raynaud's phenomenon).

      Pain and difficulty with dentures, which may lead to dental restorations

 

Symptoms of Mania - the "highs" of bipolar disorder From WebMD

      Increased physical and mental activity and energy

      Heightened mood, exaggerated optimism and self-confidence

      Excessive irritability, aggressive behavior

      Decreased need for sleep without experiencing fatigue

      Grandiose delusions, inflated sense of self-importance

      Racing speech, racing thoughts, flight of ideas

      Impulsiveness, poor judgment, distractibility

      Reckless behavior 

      In the most severe cases, delusions and hallucinations

 

Symptoms of depression - the "lows" of bipolar disorder From WebMD

      Prolonged sadness or unexplained crying spells

      Significant changes in appetite and sleep patterns

      Irritability, anger, worry, agitation, anxiety

      Pessimism, indifference

      Loss of energy, persistent lethargy

      Feelings of guilt, worthlessness

      Inability to concentrate, indecisiveness

      Inability to take pleasure in former interests, social withdrawal

      Unexplained aches and pains

      Recurring thoughts of death or suicide

  Hit Counter      

 

Hey, Calontir!



[1]Duration of exposure to gluten and risk for autoimmune disorders in patients with celiac disease. SIGEP Study Group for Autoimmune Disorders in Celiac Disease.”, Ventura A, Magazzu G, Greco L., Department of Pediatrics, University of Trieste, IRCCS Burlo-Garofolo, Trieste, Italy, Gastroenterology. 1999 Aug;117(2):297-303.